Lipase Tests

A lipase test measures the level of lipase in your blood. Lipase helps your body digest fats. It's a type of digestive enzyme.

An enzyme is a protein that speeds up certain chemical reactions in your body. Most of your lipase is made in your pancreas, an organ located behind the lower part of your stomach. Lipase is also made in your salivary (spit) glands and in your stomach.

It's normal to have a small amount of lipase in your blood. But if the cells of your pancreas are damaged, they will release larger amounts of lipase. So, high levels of lipase in your blood may mean you have pancreatitis, (an inflamed, swollen pancreas) or another type of pancreatic disease.

A lipase tests can help diagnose these conditions and others.

Why this test is done

You may need a lipase test if you have symptoms that may be caused by a problem with your pancreas. These include:

• Pain in your abdomen (belly) that may spread to your lower back
• Nausea and vomiting
• Diarrhea
• Swollen or tender belly
• Fever
• Fast heartbeat
• Jaundice, or yellowing of the skin and eyes

How to prepare

You may need to fast (not eat or drink) for 8-12 hours before a lipase blood test.

Certain medicines and supplements can affect your test results. Your provider will let you know if you need to stop taking any medicines before your test. But don't stop taking any medicines unless your provider tells you to.

Sample type

Blood

Other names for this test

serum lipase, lipase, LPS