Myoglobin Immunostain, Technical Component Only
Sourced reference. This entry is compiled from Mayo Clinic and is reproduced for reference rather than written by eMed7. Reference ranges differ between laboratories — always read a result against the range printed on your own report.
Marker of skeletal and cardiac muscle
Myoglobin is found in skeletal and cardiac muscle, but not in smooth muscle, and functions as an oxygen transporting pigment. Antibodies to myoglobin may be useful in the diagnosis of rhabdomyosarcomas, but the proportion of positive cells may be small and may be distributed unevenly in the section. Staining for myoglobin is not seen in carcinomas or in other sarcomas.
Why this test is done
This test does not include pathologist interpretation, only technical performance of the stain. If interpretation is required, order PATHC / Pathology Consultation for a full diagnostic evaluation or second opinion of the case.
The positive and negative controls are verified as showing appropriate immunoreactivity.
Interpretation of this test should be performed in the context of the patient's clinical history and other diagnostic tests by a qualified pathologist.
How to prepare
Specimen Type: Tissue
Supplies: Immunostain Technical Only Envelope (T693)
Container/Tube: Immunostain Technical Only Envelope
Preferred:
-Formalin-fixed, paraffin-embedded tissue block
OR
-2 Unstained, positively charged glass slides (25- x 75- x 1-mm) per test ordered; sections 4-microns thick
Acceptable: None
Sample type
Specimen Type: Tissue Supplies: Immunostain Technical Only Envelope (T693) Container/Tube: Immunostain Technical Only Envelope Preferred: -Formalin-fixed, paraffin-embedded tissue block OR -2 Unstained, positively charged glass slides (25- x 75- x 1-mm) per test ordered; sections 4-microns thick Acceptable: None
Other names for this test
ISMYOGLIHCTO
Full library entry
Reference ranges, sample type, and citations for this marker.
Open in the biomarker librarySources
- mayocliniclabs.com/test-catalog/overview/70517— Mayo Clinic
Track this marker over time
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Educational content only. This entry describes what a test measures and how published reference ranges are defined. It is not a diagnosis, does not interpret your personal results, and is not a substitute for a qualified doctor.